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Syntegon presents numerous innovations at ACHEMA Pulse - Insights

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Innovative answers to current pharmaceutical challenges

  • SVP Essential: cost-efficient process system with short delivery times
  • Versynta FFP: the modular small batch solution for maximum flexibility
  • Compact, patented loading system for freeze dryers
  • GKF 60: new standards in lab-scale capsule filling
  • Sepion Coater: higher flexibility in tablet coating
  • MIRA: detecting potential machine failures before they occur

Waiblingen, Germany – Ever smaller batches for individual therapeutic approaches, new cost-intensive biopharmaceuticals, and the Covid-19 pandemic are currently changing the pharmaceutical industry more rapidly than ever before. Syntegon Technology showcases solutions to these challenges at the virtual ACHEMA Pulse from June 15 to 16, 2021. "Highly flexible filling technologies with maximum yield, fast product and packaging changeovers, shorter production and delivery times, and digital technologies – these are the hot topics in the industry, and for which we present innovative answers," says Dr. Andreas Mattern, Director Global Product Management Pharma at Syntegon Technology.

SVP Essential: new basic version with short delivery times

Under the name SVP Essential, Syntegon has launched a new, cost-efficient version of its proven Pharmatec SVP process systems. Thanks to its modular design, customers receive a fully automated, ready-to-use solution for the production of small-volume liquid parenterals. Syntegon has developed a series of functional modules that can be assembled in a modular system. This reduces the engineering effort and ultimately the delivery time – to just six months. The compact system is supplied as a "package unit" with a technology skid in the clean room, enabling customers to easily install it independently. The Syntegon experts merely carry out the commissioning on site.

syntegon-pharmatec-svp-essential

The new, fully automated Pharmatec SVP Essential process system from Syntegon offers the highest hygienic standards and reproducibility throughout the entire process.
Reproduction for press purposes free of charge with credit “Picture: Syntegon”

Modular small batch solution: Versynta Flexible Filling Platform

Syntegon bundles solutions for small and micro batches in the new Versynta portfolio. The modular Versynta Flexible Filling Platform (FFP) for aseptic and highly potent liquid pharmaceuticals is individually configurable and available with an integratable isolator. It achieves high product yields at low outputs of up to 3,600 containers per hour, amongst others thanks to 100 percent in-process control. The machine can be easily converted to a wide range of containers and different filling systems. The Pharma Handling Unit ensures safe and gentle transport by transferring the containers from one station to the next without glass-to-glass contact.

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With Versynta FFP from Syntegon, pharmaceutical manufacturers, R&D laboratories and biotech startups receive a combination of standardization, high modularity and short delivery times.
Reproduction for press purposes free of charge with credit “Picture: Syntegon”

New, patented loading system for freeze dryers

With the new, patented loading system for freeze dryers, the Syntegon product brand SBM (Schoeller Bleckmann Medizintechnik) achieves considerable space savings and maximum process reliability. Thanks to the new front pusher design and its innovative drive, movement is no longer accomplished by a hydraulically operated pusher arm, but via the mechanical servo drive of the loading unit. The entire system can be installed within the isolator dimensions while the drive unit is placed outside the product handling area. This innovation saves a lot of space in the fill-finish area and avoids possible contamination. Thanks to the improved accessibility, maintenance work can be carried out quickly and without integrity loss in the isolator.

syntegon-freeze-dryer-loading-system

The new, patented loading system for freeze dryers from the Syntegon product brand SBM achieves considerable space savings and maximum process reliability.
Reproduction for press purposes free of charge with credit “Picture: Syntegon”

GKF 60 capsule filling machine: highest dosing flexibility with a small footprint

The GKF 60 sets new standards in capsule filling for laboratories. The mobile unit facilitates the development of new formulations with a wide variety of dosing systems – flexibly and at different OEB levels. Scale-up to production is also easily accomplished. With only six stations and a total of three filling stations that can be integrated in parallel, the machine is extremely compact and flexible. Even the smallest quantities from 0.1 milligram filling weight can be filled without product loss on the newly developed piezo station. Depending on the chosen version (standard, containment, or combi), the new GKF 60 is suitable for both simple and highly potent formulations from OEB3 to OEB5.

Sepion Coater: experience meets innovation

The Sepion coater series from the Hüttlin product brand features closed material handling as well as high spray rates at very low relative standard deviation (RSD). The drum can be filled with flexible batch sizes between 10 and 100 percent of the working volume. The optimized drum geometry with its sophisticated spraying system offers better guidance of the process air and shorter process times with high yields. In addition, the spray arm can be automatically adjusted for all filling heights. As a result, the new Sepion coater and its containment options ensure an optimum and reliable coating process – which is currently being implemented in the first greenfield projects in Europe and Asia.

syntegon-sepion-coater

The Sepion coater series from the Hüttlin product brand features closed material handling as well as high spray rates at very low relative standard deviation (RSD).
Reproduction for press purposes free of charge with credit “Picture: Syntegon”

MIRA: from preventive to predictive maintenance

With MIRA (Machine Intelligence Reporting & Analytics), Syntegon is taking the next step in digital services. The modular software solution developed by Syntegon for the intelligent monitoring of process-critical components makes downtimes foreseeable and ensures trouble-free production operations. For example, anomalies in fans can be detected by temperature and vibration analyses up to six weeks before a potential costly failure. As a stand-alone predictive maintenance system, MIRA operates in parallel with ongoing operations and does not interfere with machine controls.

syntegon-mira

The modular software solution MIRA, developed by Syntegon for the intelligent monitoring of process-critical components, makes downtimes foreseeable and ensures trouble-free production operations.
Reproduction for press purposes free of charge with credit “Picture: Syntegon”

Learn more about the novelties from Syntegon Technology on June 15 and 16, 2021 at ACHEMA Pulse.

About Syntegon Technology

Syntegon Technology is a leading global process and packaging technology provider. Formerly the packaging division of the Bosch Group, the company, headquartered in Waiblingen (Germany), has been offering complete solutions for the pharmaceutical and food industries for over 50 years. About 6,000 employees at 30 locations in more than 15 countries generated a total revenue of 1.3 billion euros in 2020. The portfolio of intelligent and sustainable technologies includes stand-alone machines, as well as complete systems and services. Fields of application in the pharmaceutical industry are the production, processing, filling, inspection and packaging of liquid and solid pharmaceuticals (e.g. syringes and capsules). In the food industry, the portfolio includes process technology for confectionery as well as packaging solutions for dry foods (e.g. bars, bakery products and coffee), frozen foods and dairy products.

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Spokesperson Product Communications Pharma
Syntegon Technology

Nicole König
Phone: +49 7951 402-648
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