Pharmaceutical cleaning solutions and depyrogenation tunnels

Whether you are filling liquid pharmaceuticals into vials, ampoules, or cartridges: All containers need to undergo thorough cleaning to remove product residues and other contaminants from their inner and outer sides before they can be processed in a pharmaceutical fill-finish line. To safeguard both operator and patient safety, it is crucial that this process step reliably upholds the highest hygiene standards across a variety of container types and sizes.

Following pre-cleaning, additional drying, sterilization, and depyrogenation are mandatory for many drugs and further increase product safety. The challenge: balancing high outputs and reproducibility with the protection of potentially fragile formulations and containers. Syntegon’s portfolio of compact pharmaceutical cleaning systems and depyrogenation tunnels supports pharmaceutical and biotech companies in answering these challenges.

Our HQL series relies on dry heat sterilization to help you achieve reproducible treatment quality while optimizing energy requirements via heat exchangers that recover energy. The modular, easily customizable tunnels reliably dry, sterilize, and depyrogenate pharmaceutical containers using dry heat (UDAF principle) within a single system. Unidirectional airflow ensures reproducible, fully definable, and validatable processes for a wide range of container types and sizes. Our depyrogenation tunnels are designed for gentle handling, protecting both containers and high-value products. Fully automated filter scans and container transport reduce operator intervention and further increase product safety while maintaining line speeds.