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Isolator Technology
Isolator Technology & Barrier Systems

Pharmaceutical isolator and barrier systems


Integrated air management

Our integrated air management simplifies processes, reducing costs and increasing efficiency. One of the benefits is a significant reduction in the required space on the technical floor. This results in a more optimized workspace and efficient resource allocation. In addition, our integrated air management solution eliminates the need for external interfaces to the building, reducing complexity and increasing security.


Key benefits

Integrated systems
Integrated systems
Filling machines, barrier technologies and peripheral equipment are seamlessly connected.
Safe aseptic filling
Safe aseptic filling
Maximum security trough monitored gloves, transfer ports and material locks.
Full lifecycle support
Full lifecycle support
Syntegon’s expertise covers consulting, isolator design, installation and validation.

Features of our pharmaceutical isolators & barrier systems

Our barrier systems include open RABS, closed RABS, isolators, and containment systems. They all offer you maximum flexibility for a broad range of applications, protecting products and personnel in the best possible way. While our RABS enhance the quality of everyday multi-product manufacturing in existing cleanrooms, our isolators further boost the safety of filling lines for high potent medications. 


  • Safe filling of aspectic, BSL and highly potent products
  • Qualification and validation support including cycle development
  • Intensive research for RABS, isolator and related barrier technologies

Isolator Technology - Video Series

All from one source

All pieces of an isolator filling line are manufactured and assembled at the same site.  

If you want to know more about isolators and the advantages of an integrated approach, watch the video.

Shortest biodecontamination cycle times

Fastest biodecontamination cycle times in the industry: 

  • Less than 60 minutes for a fully loaded production size isolator. 
  • Shorter cycle times mean more time in production.

Let us be your partner in barrier technology, getting you to highest equipment utilization.

Integrated air handling technology

Do you need a higher speed and higher output aseptic filler? 

Syntegon also offers air handling systems fully integrated into the plenum of our largest isolators, to make users lives easier.

Get answers to all your questions about integrated air management.

Key benefits

Explore the unique features that make Syntegon's isolator filling lines so special.
  • Integration of a comprehensive Factory Acceptance Test (FAT) for your entire production line.
  • Minimized complexity of interfaces.

Use case scenarios

Glove testing systems
The highest safety for isolators and RABS
Maintaining an aseptic production
How to transfer products into barrier systems
A challenge for sterile manufacturing
How will Annex 1 change fill/finish processes?
Syntegon and AbbVie
Taking ADC processing to the next level
RABS vs. Isolator
Choosing the right isolation technology
Fill/finish of liquid pharmaceuticals
Syntegon expands local support for import projects in North America
Aseptic and highly potent drugs
Insights into state-of-the-art sterile fill/finish applications
Service Agreements
Service Agreements

Find out more about our Service Agreements here.

Digital Solutions
Digital Solutions

Find out more about Digital Solutions here.


Find out more about Maintenance here.

Technical Support
Technical Support

Find out more about Technical Support here.


Find out more about Modernizations here.


Find out more about our Training here.

Expert Services
Expert Services

Find out more about our Expert Services here.

Why choose a Syntegon isolator / barrier system?


Isolator experts before it was fashion

Long-standing experience: We have been designing, developing and manufacturing reliable isolators for decades. Syntegon is your partner, offering valuable support across the entire lifecycle of your barrier system project. 

Seamless systems: We integrate isolators, filling machines, decontamination equipment and HVAC technology to secure highly efficient, safe processes for your aseptic processing requirements.

Process efficiency: Syntegon isolators can be used in a wide variety of settings, thanks to their highly flexible set-ups. Your benefits: high product availability, improved filling quality and reduced operating costs.

Keep human intervention to the minimum – this is the mantra in pharmaceutical production. We know exactly how to combine good operator experience with the highest safety standards. Our industry-proven barrier systems and isolator technology from a single source allow to achieve the desired separation of production and personnel in the most varied manufacturing scenarios.

years of experience 
patents and patent applications 
machines installed world-wide 

Our experts behind the scenes

“An isolator is the most consistent answer for the most stringent quality requirements in parenteral filling. Mechanics, electrics and software must all be tuned perfectly to achieve the process performance for which Syntegon isolators are known today. The expectations of our customers motivates us to deliver maximum performance!”

Dr. Johannes Rauschnabel – Head of advanced development packaging technology and chief pharma expert


Our experts behind the scenes

“For the past 20-plus years and counting, I have associated Syntegon isolators with highest process reliability, the most stringent pharmaceutical requirements, and ultimately – the lives of millions of patients impacted worldwide.”

Mathias Kreher – Sales


Our experts behind the scenes

 “With Syntegon isolators I associate short and efficient cycle times for biodecontamination.”

Annika Klenk – Project manager cycle  development/validation


Our experts behind the scenes

“Working with Syntegon isolators and their cycle development requires close coordination with our customers. The interesting discussions that result from this are very valuable because they further develop us as well as our customers.”

Carmen Riedt – Group leader and responsible for qualification 



Our experts behind the scenes

“With Syntegon isolators, I associate a great collaboration, internally as well as with many different teams from our customers.”

Michael Meyer – Team leader cycle development/validationand process development 


Our experts behind the scenes

„In line with our philosophy, the integration of air handling into filling line isolators is a major step in minimizing on-site complexity for our customers.
Our goal is to provide solutions that make our customers´ lives easier by reducing interfaces and maximizing integration.”

Lukas Munzinger - Global Product Manager Isolator Technology

Pharmaceutical isolator downloads

Isolator Systems
Isolator Systems

Safety and performance from one source.


How to design an isolated fill / finish process that protects both products and operators.


Avoiding product oxidation by H2O2 in isolators.


The past, present and future of H2O2 biodecontamination cycle times.

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Interested in our pharmaceutical isolator?

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