We support you throughout the entire machine life cycle, from spare parts management to digital line optimization. Service agreements are a key element of our portfolio structure. Together, we tailor our solutions to your individual needs. Our global network of experts supports you with maintenance planning, technical support, and modernizations, as well as operator training and end of life services. With our digital solutions, you gain control over your production processes and create transparency on product and machine data anytime, anywhere.
Capsule filling machine – GKF Containment series
GKF capsule filling containment solutions
Containment is all about operator safety. The product area is separated from the personnel area by a barrier system to prevent any negative impacts (contamination). Syntegon provides two different solutions for OSD (Oral Solid Dosage) processing under containment conditions: the ProTect (up to OEB 4) and HiProTect (up to OEB 5) execution. We further offer three different cleaning approaches for closed capsule filling machines, which you can adapt to your specific needs together with our experts.
Capsule filling machines – our GKF Containment portfolio
GKF 60 ProTect and HiProTect
R&D capsule filling machine – takes your molecule to production, even under OEB 4 or OEB 5 containment classifications.
GKF 720 ProTect and HiProTect
Provides an open and variable OEB 4 or OEB 5 platform with various features and filling stations.
GKF 1700 HiProTect
Unique containment solution that fills highly potent substances (OEB 5) and comes with an automated cleaning system.
GKF 2600 ProTect
Dry containment solution for potent pharmaceuticals up to OEB 4.
GKF 60 ProTect and HiProTectThe GKF 60, which achieves an output of up to 3,600 capsules per hour is available either in the ProTect execution based on a dedicated R&D laminar flow principle, or in the HiProTect execution with a closed door concept and glove port access. We further offer a combination of the manual dry and wet cleaning principle, or a WIP process with integrated spray nozzles.
GKF 720 ProTect and HiProTectThe GKF 720 ProTect and HiProTect provide all features and benefits of a flexible small batch production machine with outputs of between 3,000 and 43,500 capsules per hour. The capsule filling macines are equipped with an inflatable door seal, dedicated air handling, a filter concept and glove access. Cleaning can be done either with a combination of manual dry and wet cleaning or with a manual WIP process.
GKF 1700 HiProTectThe GKF 1700 HiProTect is a true containment machine, providing additional safety thanks to an own pressure zone concept. While achieving an output of up to 100,000 capsules per hour, the machine features a range of automated processes. A programmable washing system stores and recalls cleaning protocols, ensuring a reproducible cleaning result for your individual WIP process.
GKF 2600 ProTectThe GKF 2600 ProTect is ideal for a flexible product set-up and large batch production of up to 156,000 capsules per hour. It provides a dry containment solution with manual dry containment via integrated suction nozzle and an optional wetting process. It monitors negative pressure inside the production chamber and provides glove port access and an RTP option.
Our ProTect and HiProTect concepts at a glance
ProTect: Capsule filling machines in the ProTect execution can handle production processes that are classified up to OEB 4. The term „ProTect“ stands for a dry cleaning approach, with optional wetting system to reduce airborne contamination.
HiProTect: This machine series is suited for products requiring a containment classification up to OEB 5. All machines are available with a manual or automated WIP (Washing-In-Place) cleaning process.
Technical data of our GKF Containment series
|GKF 60 ProTect & HiProTect||GKF 720 ProTect & HiProTect||GKF 1700 HiProTect||GKF 2600 ProTect|
|Output||3,600 caps/h||3,000 up to 43,500 caps/h||100,000 caps/h||156,600 caps/h|
|Machine cycles||Max. 60 cycles/min||Max. 145 cycles/min||Max. 140 cycles/min||Max. 145 cycles/min|
|Dimensions (HxWxD)||1,900 x 1,000 x 900 mm||3,490 x 3,133 x 2,101 mm||2,044 x 2,036 x 2,390 mm||3,548 x 3,178 x 2,436 mm|
According to customer specification
380-480 V, 50/60 Hz
400 V ±10% , 50/60 Hz
380 – 480 V, 50/60 Hz
Why choose Syntegon as your partner?
Processing and packaging for a better life – this is what our employees work for every day. Looking back on a 160 years of experience, the portfolio of intelligent, innovative and reliable solutions help our customers in the global pharmaceutical and food industries to improve people‘s life.
With 1,100 service experts and a comprehensive service portfolio throughout the entire machine lifecycle from spare parts management to digital line optimization, Syntegon lays the foundation for smooth production processes for all customers.
Why capsule sealing?
Capsule sealing with banding technology ensures the highest product quality and prevents liquid-filled capsules from leakage. Banding also provides an additional measure for anti-counterfeiting of capsules filled with powder or other components. Sealing provides an enhanced safety measure to meet regulatory requirements. Our Syntegon GKB 2100 banding machine can handle both hard gelatine and HPMC (plant-based) capsules.
The Syntegon GKB 2100 banding machine
The new GKB 2100 features a particularly robust and flexible process, combined with the highest yield and maximum process stability. The focus is on user-friendliness, as well as very good accessibility for cleaning and easy format part changeovers. Our banding machine achieves an output of up to 125,000 capsules per hour.
Capsule filling downloads
A brief overview of Syntegon’s GKF capsule filling containment solutions
Industry requirements and Syntegon’s containment solutions for OSD forms
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