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    RTU filling for cartridges from clinical to high output

    Cut changeover and Grade A touchpoints with gloveless isolators, robotics, and 100% in‑process control.

    Explore our RTU cartridge solutions

    Overall 5 Solutions
    Output performance
    Format range
    Special features
    Changeover
    Filling systems
    Container types
    Barrier technologies and line integration
    Benefits
    Versynta_microbatch
    Versynta microBatch
    Output performance
    Up to 500/h (nest)
    Format range
    Vials 2R-50R, plus syringes 0.5-20 ml, cartridges 1-10 ml
    Special features
    Gloveless isolator, fully automated robotic cell, 100% in‑process control
    Changeover
    Fast batch‑to‑batch changeovers
    Filling systems
    Peristaltic, rolling diaphragm
    Container types
    Syringes, vials, cartridges
    Barrier technologies and line integration
    Gloveless isolator, integrated air management
    Benefits

    Best if you want:

    • a gloveless micro‑batch cartridge cell
    • short biodecontamination and fast changeovers
    • minimized product loss
    Brochure
    1080x720_VersyntaFFP
    Versynta FFP
    Output performance
    Up to 3,600/h
    Format range
    Cartridges 1–10 ml, syringes 0.5–10 ml, vials 2R–50R
    Special features
    100% in‑process control, isolator with integrated air management
    Changeover
    Size‑parts only, no module exchange
    Filling systems
    Peristaltic, piston, rolling diaphragm; vacuum filling and stoppering
    Container types
    Syringes, vials, cartridges
    Barrier technologies and line integration
    Isolator with integrated air management
    Benefits

    Best if you want:

    • RTU cartridge capacity up to 3,600 cph with 100% IPC
    • One platform for cartridges plus syringes and vials
    Brochure
    1080x720_FXSCombi
    FXS Combi
    Output performance
    Low, medium or high output rates
    Format range
    Cartridges 3–10 ml, syringes 0.5–20 ml (50 optional); vials 2R–20R (25R, 30R optional)
    Special features
    Fully automatic in‑process control; vacuum filling and stoppering
    Changeover
    Easy, quick format changes
    Filling systems
    Peristaltic; vacuum filling and stoppering
    Container types
    Syringes, vials, cartridges
    Barrier technologies and line integration
    Isolator with integrated air management
    Benefits

    Best if you want:

    • size‑part only changeovers across containers
    • 100% in‑process control on all format
    • easy lyophilization integration
    Brochure
    1080x720_MLDAdvanced
    MLD Advanced
    Output performance
    Up to 400/min
    Format range
    Cartridges 1–3 ml, syringes 0.5–10 ml, vials 2R–30R
    Special features
    100% in‑process control, modular conveyor, tub and nest handling
    Changeover
    Tool-free changeover
    Filling systems
    Multiple options including vacuum filling
    Container types
    Syringes, vials, cartridges
    Barrier technologies and line integration
    Annex 1 compliant, flexible L or U layouts
    Benefits

    Best if you want:

    • Annex 1 compliant high‑speed cartridges
    • a modular conveyor to add stations like gassing or beading
    • flexible L or U layouts
    Brochure
    1080x1080_syntiso-1
    SynTiso
    Output performance
    Up to 600/min
    Format range
    Cartridges 1–20 ml, syringes 0.5–20 ml, vials 2R–50R
    Special features
    Gloveless isolator, frictionless transport, 100% in‑process control
    Changeover
    Automated aseptic set‑up functions
    Filling systems
    Peristaltic, piston, time‑pressure, vent tube or vacuum stoppering
    Container types
    Syringes, vials, cartridges
    Barrier technologies and line integration
    In‑air gloveless isolator, RackSter sterile parts transfer, connects lyophilization and inspection
    Benefits

    Best if you want:

    • an in‑air gloveless isolator with frictionless transport
    • RackSter sterile parts transfer and BFPC integration
    • OEE improvement >35%
    Brochure

    RTU Cartridge lines from small batches up to 600/min with 100% IPC

    1080x1080_MBFront

    Up to 500 cartridges/h in a gloveless micro cell

    Run micro batches without tying up large lines.
    1080_1080_FXSCombi

    One platform for cartridges, vials and syringes

    Add cartridge capacity without new lines.
    1080x1080_SynTiso008

    600 cartridges/min without gloves

    Confirm every unit at speed in a gloveless isolator.

    Explore related solutions for RTU cartridge filling

    1080x720_Trayloading
    Tray loading
    1080x720_DSF0100
    Filling systems
    1080x720_VisualInspection
    Visual inspection

    Your strategic lifecycle partner for RTU filling

    service-life-cycle
    Lifecycle and Annex 1 consulting for RTU lines

    Plan RTU projects with experts who know Annex 1 from URS to qualification. Service agreements, training and digital support keep performance stable across the lifecycle. 

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    service-life-uptime
    Secure availability – every day

    Fast spare parts, qualified support, and preventive maintenance help you avoid unplanned downtime, protect performance, and keep daily operations reliable.

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    service-future-ready
    Make your line fit for tomorrow

    Scalable retrofits and data solutions help you adapt to new demands, improve OEE, and keep your lines future-proof across changing requirements.

    Learn more
    Featured_Download_Teaser_RTU

    Plan your RTU filling portfolio with confidence

    See all Syntegon RTU filling options by output and container.

    • Match batch size to output
    • Compare RTU machines for each container
    • Check Annex 1 ready and IPC features
    Download
    1080x1080_syntiso-1
    Innovation Spotlight

    SynTiso gloveless RTU line for high speed filling

    See how SynTiso combines a gloveless isolator and up to 600 containers per minute for large RTU campaigns.

    Explore SynTiso

    Ready to use filling knowledge hub

    Explore all RTU filling machines
    Explore all RTU filling machines

    Get an in-depth overview of advanced RTU filling solutions designed for syringes, vials, and cartridges.

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    Explore SynTiso – the next evolution.
    Explore SynTiso – the next evolution.

    Learn more about SynTiso, the gloveless solution, that combines regulatory compliance with cutting-edge technology.

    Download
    Small and micro batch whitepaper
    Small and micro batch whitepaper

    Learn how small and micro batches are changing pharmaceutical processes.

    Download

    Frequently asked questions

    RTU cartridges fit high-value products and frequent small batches. Pre-sterilized, nested containers reduce cleaning and sterilization work. With gloveless isolators and 100% in-process control on suitable platforms, you cut Grade A interventions and verify each unit.

    Ranges depend on the platform. Portfolio coverage includes 1–3 ml, 3–10 ml, and up to 1–20 ml. Typical heights span 35–95 mm and diameters 8.65–26.5 mm. Confirm exact ranges during configuration.

    • Versynta microBatch: up to 500/h

    • Versynta FFP: up to 3,600/h

    • FXS Combi: low, medium or high rates

    • MLD Advanced: up to 400/min

    • SynTiso: up to 600/min.

    Select by batch size, integration needs and barrier concept.

    Download portfolio overview

    Gloveless isolators reduce interventions in Grade A. Barrier systems such as RABS or isolator, frictionless transport and automated setups add control. Features vary by machine and configuration.

    Find out more

    Yes. FXS Combi processes nested syringes, vials and cartridges on one machine. MLD Advanced and SynTiso run all RTU container types at higher outputs. Versynta FFP supports all container types with size-part changeovers only.

    Interested in filling RTU cartridges, syringes & vials?

    Interested in filling RTU cartridges, syringes & vials?

    Talk to a Syntegon expert to learn more about RTU filling solutions.

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