Discover seamless solutions for diabetes and obesity treatment with GLP-1 therapies. We support your needs from processing to assembly and inspection.
Key takeaways
- Strong growth in GLP-1 therapies, with up to 100 million patients by 2030
- Cartridge-based pens require sterile, high-output, and seamless production processes
- Syntegon’s proven expertise supports GLP-1 production globally
By 2030, around 100 million people are expected to be treated with advanced GLP-1 medicines. They continue to represent one of the fastest-growing self-medication markets worldwide. Some of the high-dose, subcutaneously injectable medications only need to be administered once a week; further developments are already underway. Originally developed for the treatment of Diabetes Type 2, GLP-1 drugs are now also used as anti-obesity medicines, while further potential long-term benefits for heart, kidney, and liver health are currently being researched.
Seamless processing of cartridge-based pens
A large part of these GLP-1 drugs is administered through pens. Cartridges, which are the main component of self-medication pens, present pharmaceutical manufacturers and CDMOs with specific challenges: They must ensure sterile individual filling, which includes flexible assembly and inspection in addition to high output – as well as additional upstream processes such as formulation, cleaning, siliconization, and sterilization. In the case of large-volume ready-to-use (RTU) cartridges, the same systems can be adapted, resulting in leaner processes without the upstream steps.
Currently, many high-speed lines are being installed for GLP-1 drug processing, while many pharmaceutical manufacturers as well as CDMOs are expanding their capacities. Of course, Syntegon is not only ready to support but already has a proven track record of installed machines and lines in the field. As a strategic lifecycle partner, our long-standing expertise enables us to support producers of diabetes and anti-obesity drugs with seamless and integrated technologies across the value chain – from processing to filling and sealing to inspection, assembly, and beyond.
The process steps at a glance
- Pure media generation
- Formulation
- Cleaning & siliconization
- Sterilization
- Filling & closing
- Barrier systems
- Inspection
- Pen assembly
- After-sales services & upgrades
Let’s fight diabetes and obesity together!
145 cartridge filling lines, including 60 high-speed lines with outputs of up to 600 containers per minute deliver the proof: Customers all over the world trust in Syntegon for seamless cartridge solutions. Whether you are already selling your GLP-1 drugs or are currently applying for marketing authorization, our experts are at your side. Let’s discuss your requirements and co-create your ideal line solution – and fight diabetes and obesity together!
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