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In sterile pharmaceutical production, precision and reliability are critical. Whether you're filling high-potency drugs or sensitive biologics, Syntegon’s advanced pharmaceutical filling machines are built to meet the toughest industry demands, helping you stay compliant, efficient and competitive.
We combine proven technology with smart automation and digital tools to support your production goals. From aseptic accuracy to full process transparency, our solutions are designed to solve real challenges and deliver lasting value.
Click the contact or download button below to speak with our experts or access our brochure and see how Syntegon’s filling systems can elevate your operations.
Connect with an expert Download our brochureFilling biotechnologically produced active ingredients places special demands on pump technology.
Our user-friendly peristaltic pump ensures gentle operation and precise dosing of cost-intensive products. As it does not require any format parts except for the hoses, the system can be operated with one hand using clip connectors. Thanks to these versatile features, the peristaltic pump is ideal for the use in barrier systems according to the EU GMP Annex 1 guidelines.
What’s more, this pump type is particularly suited for single-use applications.
Benefits:
The rotary valve piston pump is extremely flexible and can be used for a wide range of applications. Its volumetric operating principle ensures high dosing accuracy for both aqueous and highly viscous liquids.
The ceramic version of the pump can also be used to fill hot and abrasive products.
The optional Smart Pump variant ensures maximum process reliability and precision while opening up new possibilities for predictive maintenance.
Benefits:
The rolling diaphragm pump combines the advantages of the peristaltic and rotary valve piston pumps. It offers gentle product handling thanks to the absence of shear contours combined with the dosing precision of a volumetric filling system.
The pump’s flexible diaphragm gently conveys the product through a piston and the pump body.
The technology is available both as a CIP/SIP and a single-use version to meet very demanding production requirements.
Benefits:
The increasing demand for space-saving machines with barrier systems requires ever more compact filling systems. This is especially true for the high-performance range and the use of a large number of filling stations. Thanks to its space-saving design, the time-pressure filling system ideally meets these requirements.
In connection with a minimum of moving mechanical parts, an intelligent algorithm enables gentle and precise filling.
Benefits:
A mass-flow sensor operating according to the Coriolis principle in each filling section ensures 100% in-process control and precise filling operations.
This sophisticated sensor technology further enables the system to manage demanding tasks such as hot and cold filling.
Benefits:
Our innovative Smart Pump provides full transparency. State-of-the-art RFID technology transmits pump-specific parameters such as cleaning status, serial number, and correction values to the filling machine via a reading device. This allows operators to read the visualized data on the machine’s HMI conveniently and reliably.
Benefits:
Filling different products with specific properties often requires more than one filling system. Our patented combi filling stations can combine several filling systems on one machine, allowing you to flexibly adapt your production line at any time.
Benefits:
Syntegon’s single-use technology, known as PreVAS in the U.S., transforms sterile liquid pharmaceutical filling. PreVAS stands for pre-validated, pre-assembled and pre-sterilized, a fully customizable, ready-to-use fluid path with extensive regulatory validations. Delivered gamma-sterilized and fully assembled, it integrates easily with most Syntegon filling machines and supports both peristaltic and rolling diaphragm pumps. PreVAS enables fast batch changeovers, reduces time to market, and offers high production flexibility.
Benefits:
No cleaning or sterilization of reusable equipment
Prevents cross-contamination between batches
Minimizes operator exposure to potent products
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Patented innovation: Our in-house technologies like the rolling diaphragm pump and combi station offer precise, gentle filling and flexibility for a wide range of containers and products.
These solutions are designed to ensure product integrity, reduce waste, and support high-quality pharmaceutical production.
Leading portfolio: With the broadest range of filling systems on the market, Syntegon enables full customization to meet your specific production needs, from small batches to high-speed lines. Our modular systems allow for easy upgrades and seamless integration into existing production environments.
Digital integration: Built-in digital solutions provide real-time process monitoring and full data transparency, supporting compliance, efficiency, and control throughout your operations.
The innovative filling solution
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