Ampoule filling machines

When it comes to bioprocessing, the systems from Syntegon’s subsidiary Pharmatec flexibly support the production of small and large volume parenterals (SVP/LVP) and infusions (IV). The process solutions comprise modular set-ups of temperature-controlled stainless-steel tanks that can be assembled to meet customer-specific settings. The new, cost-efficient SVP Essential is a fully automated, ready-to-use system to produce simple parenterals such as analgesics, insulin, and generic drugs.

Benefits:

• Adaptable to specific room conditions and floor plans
• Continuous process monitoring for the highest possible safety
• Suitable for toxic substances up to OEB5 in isolators
• SVP Essential: less engineering effort, faster delivery times

Before and after filling, vials, ampoules, syringes, and cartridges require thorough internal and external cleaning to remove residues and contaminants. This step is key to protecting operator and patient safety. Syntegon’s compact cleaning systems cover low to high output ranges and support efficient, hygienic processing.

Designed for a wide range of containers, the systems focus on fast, user-friendly operation with ergonomic design.

Benefits:

• Nearly complete surface cleaning

• Use of various cleaning agents

• Integration into Syntegon barrier systems possible

Ampoules require reliable inspection to ensure patient safety. Syntegon offers manual to fully automated systems for detecting particles and container defects in liquid and lyophilized products, using visual inspection and advanced CCIT like HVLD, static division, and headspace analysis. Inline systems enable real-time defect detection.

Benefits:

• Up to 36,000 units/hour (AIM series)

• Camera and light transmission inspection

• Patented CCIT technology

• Modular design for fast setup

• Inline detection for higher safety

The Syntegon company SBM (Schoeller-Bleckmann Medizintechnik) offers a vast portfolio of versatile sterilization solutions for an effective treatment of porous loads and liquids in open, semi-sealed or closed containers. The vacuum-steam, steam/air mixture and hot water shower processes support you in achieving reproducible equipment and terminal sterilization while optimizing your energy requirements.

• Wide process range
• Hygienic design
• Flexible recipe editor for customized processes
• Automatic in-line filter sterilization