TPR 500

Outstanding productivity and Usability

The TPR 500 tablet press is equipped with several technical innovations and offers customers the highest machine quality combined with excellent usability.

The TPR 500 is equipped with a new 56-station die table and can produce more than 400,000 tablets per hour, considerably reducing process and production time. The modular powder feeding system allows for more flexibility with a two-paddle design that can easily be upgraded to three paddles, depending on product properties and powder characteristics. The machine's good overall accessibility promotes easy tool changes and cleaning. Turret removal is possible in only ten minutes, while complete product changeover can be achieved in less than one hour.

"True Flow" Tablet Discharge Chute

The “True Flow” tablet discharge chute features an easy-to-clean pneumatic gate mechanism and an optimized take-off angle, significantly reducing product damage and increasing output, especially with shaped or friable tablets.

Connected directly to the turret, the new torque drive even achieves high torque at low revolutions per minute (rpm) while saving space in the mechanical area. It generates little heat and has no wear and tear parts, allowing customers to considerably reduce maintenance.

Outstanding hygienic design

The Syntegon TPR 500 is designed for ease of use, good accessibility and reduced cleaning efforts. The two-level production zone ensures total separation of the production and technical areas – even when the turret is removed.


  • Fastest changeover from product A to product B
  • Excellent feeder technology in two and three paddle execution
  • Life cycle cost extremely low
  • Best in class OEE
  • Designed for effective cleaning
  • State-of-the-art, off-the-shelf Beckhoff controls, Syntegon software package running on Windows 10
  • Best process “visibility”
  • Containment concept (OEL level 4: 1–10 μgr/m³) – optionally
  • Best tablet quality due to stress-free “True Flow” discharge system
  • MUPS-ready (Multiple Unit Pellet System) machine and feeder execution
  • Technical Data
    Technical Data
      Standard Die Plates Integrated Die Plates
    Number of Stations 32 32 39 50 56 39 56
    Punch Type 32 D *** 32 441 *** 39 B 50 BB 56 BBS 39 D *** 56 B
    PCD [mm] 470 470 470 470 470 470 470
    Max. turret speed [rpm] 100 90 120 120 120 100 120
    Max. output – tablets/minute 3200 2875 4675 6000 6700 3900 6700
    Max. output * – tablets/hour 192000 172500 280500 360000 402000 234000 402000
    Max. tablet diameter [mm] 25 25 16 ** 13 11 25 16 **
    Max. primary compression force (kN) 100 100 100 100 100 100 100
    Max. main compression force (kN) 100 100 100 100 100 100 100
    Max. filling depth [mm] 21 21 18 18 18 21 18

    * The output depends on tablet size and product characteristics
    ** Larger tablets possible on request
    *** Higher output possible on request, depending on punch geometrie and product characteristics
    Technical data are subject to change

    TPR 500 - innovative design and high productivity

    • 403,000 tablets output per hour
    • Modular powder feeding system
    • New “True Flow” tablet discharge chute for smooth product delivery
    • New Torque drive
    • HMI for an excellent usability
    • GMP
    • Exceptional usability and maintenance
    • Integrated die plate
  • Request for Quote

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  • Application Examples

    Typical Applications:

    • Medium to large scale batch production
    • Prescription, Generic or OTC Pharmaceutical products
    • Nutraceutical (vitamins, health food supplements)
    • Direct compression
    • Medicated lozenges
    • Catalysts
    • MUPS
  • Parts and Service

    Innovative services tailored to your needs

    A comprehensive service portfolio lays the foundation for smooth production processes. We at Syntegon support you throughout the entire machine life cycle, from spare parts management to digital line optimization. Service agreements are a key element of our portfolio structure. We minimize production risks and we maximize the efficiency of your equipment by working with you as equal partners.

    Together, we tailor our solutions to your individual needs. You benefit from fixed conditions and guaranteed services. Our global network of experts supports you with maintenance planning, technical support, and modernizations, as well as operator training and end-of-life services. With our digital solutions, you gain control over your production processes and create transparency on product and machine data – anytime, anywhere.

    Go to Syntegon Technology Services

    Service and Digital Solutions

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