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Bulk Vial Liquid Filling

Vial filling machines

filling-of-vials
Filling of vials in bulk

Pharmaceutical manufacturers have been trusting Syntegon for more than 60 years to process their vials reliably, safely, and efficiently. We have installed more than 1,500 vial filling and closing machines all over the world. They are used to process some of the most valuable and urgently needed pharmaceutical liquids in 24 hour operations, for instance the new Covid-19 vaccines, oncology preparations or other biopharmaceuticals. Either as a classical bulk process with washing and depyrogenation tunnel, or in combination with ready-to-use (RTU) vials in trays – we support you with our comprehensive knowledge and technical solutions.

Key benefits

Fast
High-speed lines with outputs up to 750/min with a reduced number of size parts support minimal changeover times.
Scalable
From small quantities to large production batches, our systems support you with any production need.
Flexible
A large range of filling volumes and technologies allows you to address changing manufacturing requirements.

Vial filling machines and features

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The appropriate filling technology for your product

The perialistic pump, for example, is a displacement pump, which presses the product through the filling hoses by means of mechanical hose deformations.

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Combine filling technologies according to projects

Our Combi filling station is a highly flexible filling platform, which enables you to use multiple filling technologies and dosing units in a small space. Start with one filling system and retrofit with another or even more, just as your projects require.

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Inline inspection solutions

During the filling process, inline inspection systems for empty vials, stopper position or crimp quality further increase product quality and maximize product yield.

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Cross-process solutions (KIV)

Our KIV facilitates the tracking and identification of each filled and sealed vial and brings benefits in product safety. Protection against counterfeiting is especially successful when combined with SODA for single object data coding of every single vial within the primary packaging process.

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Outstanding machine design

Our machines all feature a clean and hygenic design for easy cleaning operations and the highest operator safety.

Our solutions for vial liquid filling

The FLC 3000 has set trends and delivered proof in many customer applications: its unique combination of flexibility and compact design have made it the preferred choice for safe and efficient filling and closing of vials and infusion bottles in the medium and high output range: 600 vials per minute are possible with a filling range of 0.2 to 500 milliliters. This is achieved with only three format part sets and minimal changeover times. No pharmaceutical filler was built more often as the FLC – with more than 650 installations worldwide.

Benefits: 

  • High process safety and reliability thanks to proven technology 
  • Wide processing area: filling range from 0.2 to 500 ml with only three sets of size parts 
  • Compact GMP-compliant machine design for medium and high output rates 
FLC-3000
Expert Services
Expert Services

We support you throughout the entire machine life cycle, from spare parts management to digital line optimization. Service agreements are a key element of our portfolio structure. Together, we tailor our solutions to your individual needs. Our global network of experts supports you with maintenance planning, technical support, and modernizations, as well as operator training and end of life services. With our digital solutions, you gain control over your production processes and create transparency on product and machine data anytime, anywhere.

Maintenance & Support
Maintenance & Support

Spare Parts
Spare Parts

Why choose a Syntegon vial filling machine?

about-us

About us


Pack style cracks: vials or bottles come in different shapes and sizes – and with specific challenges. We help you find the matching processing equipment.

Customizable solutions: modularity is a built-in characteristic of our bulk processing solutions. They perfectly blend into your production environment.

Full process expertise: from filling to closing and freeze drying, we have got you covered with a comprehensive portfolio. 

years of experience 
patents and patent applications 
machines in the installed base 
locations 

Vial filling downloads

Vaccine production system
Vaccine production system

Together in the fight against Covid-19: uur complete vaccine production systems at a glance

Vial liquid portfolio
Vial liquid portfolio

Learn more about our vial liquid portfolio

Pushing the envelope for pre-sterilized vials
Pushing the envelope for pre-sterilized vials

An industry-first series of experiments to investigate Vaporized Hydrogen Peroxide (VHP) decontamination

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