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RTU Upstream Handling

Ready-to-use upstream handling systems


Efficient and safe handling is crucial right from the start of your aseptic filling process. Our upstream handling systems support tub and bag opening, de-nesting and filling of different RTU containers.

While our ATO automatic tub opener and ABO automatic bag opener platforms ensure safe removal, various filling systems for pre-sterilized packaging combine flexibility and precision. The systems are easily adaptable to small, medium, and high output production of liquid and freeze-dried medicines.

Key benefits

High safety
Bags are removed fully automatically without touching the tub surface
High speeds
ATO and ABO solutions are suited for high, medium, and low output applications
High precision
Different filling technologies ensure accurate filling of different packaging types

Features of our RTU upstream handling systems

Automated bag and tub opening are a permanent fixture of aseptic processing. Our fully automated solutions secure product safety right from the start: they minimize operator contact and contamination risks. Prior to de-nesting, the ABO/ATO platforms remove RTU packaging tubs from their bags, securing steady throughput into high-speed, medium and low output applications.

  • Bag opening without tub contact
  • Easy integration into existing line concepts
  • Reproducible processes for reliable bag/tub handling
Service Agreements
Service Agreements

We support you throughout the entire machine life cycle, from spare parts management to digital line optimization. Service Agreements are a key element of our portfolio structure. Together, we tailor our solutions to your individual needs. Our global network of experts supports you with maintenance planning, technical support as well as operator training and end of life services. With our digital solutions, you gain control over your production processes and create transparency on product and machine data anytime, anywhere.

Maintenance & Support
Maintenance & Support

Spare Parts
Spare Parts

Why upstream processing with Syntegon?


About us

  • Aseptic operations: Highly automated, isolator-compatible solutions reduce operator intervention and contamination risks.
  • Safe processing: Gentle container handling keeps pre-sterilized syringes, cartridges and vials and their contents safe at all times.
  • Technological flexibility: A multitude of filling systems is available for different containers and product requirements.

Ready-to-use packaging poses several challenges, but none that we couldn’t meet: from aseptic bag and tub opening to efficient de-nesting and flexible, state-of-the-art filling technologies, we have what it takes to boost your upstream handling. Our decades of industry experience makes Syntegon a partner you can trust, be it as engineering experts, service professionals or consultants.

years of experience 
patents and patent applications 
machines installed world-wide 

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