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Pharmaceutical isolator and barrier systems

High-performance pharmaceutical isolator by Syntegon with integrated glove ports and advanced containment for sterile drug manufacturing environments

Integrated air management

In aseptic manufacturing, GMP compliance, operator and product safety as well as efficiency and space are essential, especially related to isolators and barrier systems.  Syntegon’s integrated air management simplifies processes, reduces costs and significantly cuts the required space on the technical floor, enabling better resource allocation and a more flexible workspace.

By removing the need for external building interfaces, our solution reduces complexity and increases security. As part of Syntegon’s pharmaceutical isolator and barrier systems portfolio, it supports efficient, compliant and streamlined operations.

Click the contact or download button below to learn how our air management solution can enhance your setup and deliver long-term value.

Connect with an expert  Download our brochure
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Key benefits

Integrated systems
Integrated systems
Filling machines, barrier technologies and peripheral equipment are seamlessly connected.
Safe aseptic filling
Safe aseptic filling
Maximum security trough monitored gloves, transfer ports and material locks.
Full lifecycle support
Full lifecycle support
Syntegon’s expertise covers consulting, isolator design, installation and validation.

Features of our pharmaceutical isolators & barrier systems

Our barrier systems include open RABS, closed RABS, isolators, and containment systems. They all offer you maximum flexibility for a broad range of applications, protecting products and personnel in the best possible way. While our RABS enhance the quality of everyday multi-product manufacturing in existing cleanrooms, our isolators further boost the safety of filling lines for high potent medications. 

Benefits:

  • Safe filling of aspectic, BSL and highly potent products
  • Qualification and validation support including cycle development
  • Intensive research for RABS, isolator and related barrier technologies
Close-up of Syntegon pharmaceutical isolator with glove ports and touchscreen control panel for sterile and automated drug processing

Isolator Technology - Video Series

All from one source

All pieces of an isolator filling line are manufactured and assembled at the same site.  

If you want to know more about isolators and the advantages of an integrated approach, watch the video.

Shortest biodecontamination cycle times

Industry-leading biodecontamination times: Under 60 minutes for a fully loaded production isolator for more uptime, higher productivity.

Partner with us for maximum efficiency in barrier technology.

Integrated air handling technology

Syntegon offers fully integrated air handling systems built into the plenum of our largest isolators to simplify your operations.

Get answers to all your questions about air management.

Key benefits

Explore the unique features that make Syntegon's isolator filling lines so special.
  • Integration of a comprehensive Factory Acceptance Test (FAT) for your entire production line.
  • Minimized complexity of interfaces.

Use case scenarios

rabs-pharma
Glove testing systems
The highest safety for isolators and RABS
pharma-containment
Maintaining an aseptic production
How to transfer products into barrier systems
pharmaceutical-isolator-manufacturer-01
A challenge for sterile manufacturing
How will Annex 1 change fill/finish processes?
pharma-isolator
Syntegon and AbbVie
Taking ADC processing to the next level
isolator
RABS vs. Isolator
Choosing the right isolation technology
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Aseptic and highly potent drugs
Insights into state-of-the-art sterile fill/finish applications
Service Agreements
Service Agreements

Find out more about our Service Agreements here.

Digital Solutions
Digital Solutions

Find out more about Digital Solutions here.

Maintenance
Maintenance

Find out more about Maintenance here.

Technical Support
Technical Support

Find out more about Technical Support here.

Modernizations
Modernizations

Find out more about Modernizations here.

Training
Training

Find out more about our Training here.

Expert Services
Expert Services

Find out more about our Expert Services here.

Why choose a Syntegon isolator / barrier system?

Interior view of Syntegon pharmaceutical isolator showcasing precision filling equipment and sterile automation components

Isolator experts before it was fashion


Long-standing experience: With decades of expertise in designing and manufacturing isolators, Syntegon supports you throughout the entire lifecycle of your barrier system project.

Seamless systems: We integrate isolators, filling machines, decontamination units, and HVAC technology to ensure safe, efficient aseptic processes.

Process efficiency: Flexible system configurations enable use in diverse environments, ensuring high product availability, improved filling quality, and lower operating costs.

Minimal human intervention: In pharma production, limiting operator interaction is key. Syntegon combines user-friendly design with top safety standards. Our proven isolator solutions enable reliable separation of personnel and product in various manufacturing settings.

years of experience 
patents and patent applications 
solutions installed worldwide 
locations 
Lukas-Munzinger

Our experts behind the scenes

„In line with our philosophy, the integration of air handling into filling line isolators is a major step in minimizing on-site complexity for our customers.
Our goal is to provide solutions that make our customers´ lives easier by reducing interfaces and maximizing integration.”

Lukas Munzinger - Global Product Manager Isolator Technology

pharmaceutical-isolator-expert

Our experts behind the scenes

“An isolator is the most consistent answer for the most stringent quality requirements in parenteral filling. Mechanics, electrics and software must all be tuned perfectly to achieve the process performance for which Syntegon isolators are known today. The expectations of our customers motivates us to deliver maximum performance!”

Dr. Johannes Rauschnabel – Head of advanced development packaging technology and chief pharma expert

we-are-highly-trusted2

Our experts behind the scenes

“For the past 20-plus years and counting, I have associated Syntegon isolators with highest process reliability, the most stringent pharmaceutical requirements, and ultimately – the lives of millions of patients impacted worldwide.”

Mathias Kreher – Sales

isolator-technology-&-barrier-systems-expert-02

Our experts behind the scenes

 “With Syntegon isolators I associate short and efficient cycle times for biodecontamination.”

Annika Klenk – Project manager cycle  development/validation

isolator-technology-&-barrier-systems-expert-03

Our experts behind the scenes

“Working with Syntegon isolators and their cycle development requires close coordination with our customers. The interesting discussions that result from this are very valuable because they further develop us as well as our customers.”

Carmen Riedt – Group leader and responsible for qualification 

 

isolator-technology-&-barrier-systems-expert

Our experts behind the scenes

“With Syntegon isolators, I associate a great collaboration, internally as well as with many different teams from our customers.”

Michael Meyer – Team leader cycle development/validationand process development 

Pharmaceutical isolator downloads

Isolator Systems
Isolator Systems

Safety and performance from one source.

Whitepaper
Whitepaper

How to design an isolated fill / finish process that protects both products and operators.

Whitepaper
Whitepaper

Avoiding product oxidation by H2O2 in isolators.

Whitepaper
Whitepaper

The past, present and future of H2O2 biodecontamination cycle times.

pharmaceutical-isolator-contact

Interested in our pharmaceutical isolator?

Contact us

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